Publications

2015

L Takacs:Plasma Epitome Profiles Are Specific for Early Stage Lung Cancer
Journal Of Thoracic Oncology 2015; 10 (9), S786-S786

Z Weiszhar, M Cserhalmi, AI Csincsi, J Lazar, L Takacs, M Jozsi: Novel monoclonal antibodies against human factor H allow mapping of functional domains and binding sites of autoantibodies. Molecular Immunology 2015;67 (1), 191-191

2014

Székely A, Szekrényes A, Kerékgyártó M, Balogh A, Kádas J, Lázár J, Guttman A, Kurucz I, Takács L.: Multicapillary SDS-gel electrophoresis for the analysis of fluorescently labeled mAb preparations: a high throughput quality control process for the production of QuantiPlasma and PlasmaScan mAb libraries. Electrophoresis. 2014 Aug;35(15):2155-62. (doi: 10.1002/elps.201400208.)

Hajdú I, Flachner B, Bognár M, Végh BM, Dobi K, Lőrincz Z, Lázár J, Cseh S, Takács L, Kurucz I.:Monoclonal antibody proteomics: use of antibody mimotope displaying phages and the relevant synthetic peptides for mAb scouting.
Immunol Lett. 2014 Aug;160(2):172-7. (doi: 10.1016/j.imlet.2014.02.001.)

Nagy B Jr, Bhattoa HP, Steiber Z, Csoban M, Szilasi M, Mehes G, Muller M,
Lazar J, Kappelmayer J, Antal-Szalmas P. Serum human epididymis protein 4 (HE4)
as a tumor marker in men with lung cancer.
Clin Chem Lab Med. 2014 Nov;52(11):1639-48. (doi: 10.1515/cclm-2014-0041.)

2013

Kovács A, Patai Z, Guttman A, Kádas J, Takács L, Kurucz I.:Fractionation of the human plasma proteome for monoclonal antibody proteomics-based biomarker discovery 2: antigen identification by dot-blot array screening. Electrophoresis. 2013 Nov;34(20-21):3064-71. (doi: 10.1002/elps.201200677.)

Kerékgyártó M, Fekete A, Szurmai Z, Kerékgyártó J, Takács L, Kurucz I, Guttman A.:Neoglycoproteins as carbohydrate antigens: synthesis, analysis, and polyclonal antibody response.Electrophoresis. 2013 Aug;34(16):2379-86. (doi: 10.1002/elps.201300052)

Váradi C, Mittermayr S, Szekrényes Á, Kádas J, Takacs L, Kurucz I, Guttman A: Analysis of haptoglobin N‐glycome alterations in inflammatory and malignant lung diseases by capillary electrophoresis Electrophoresis.2013; 34 (16), 2287-2294 (doi: 10.1002/elps.201300041)

Szebeni, J. , Weiszhár, Z. , Rozsnyay, Z. , Martinsky, T. , Kádas, J. , Lázár, J. , Takács, L. and Kurucz, I.:Plasma Proteome Profiling with Monoclonal Antibody Libraries: A Pilot Biomarker Analysis for Nanomedicine-Induced Complement Activation. Advances in Nanoparticles,2013; 2, 133-144. (doi: 10.4236/anp.2013.22022.)

M.Racz, L.Takacs, A.Guttman, J.Lazar: Removal of abundant proteins to enable global proteome analysis of the human plasma: QC methodology development using immunoglobulin and albumin as markers, Chemicke Listy, 2013; 107 S428-S429.

Darvas, F., Guttman, A., Dormán, G., Takács, L., Debreceni, A. and Kurucz, I., 2013. Genomic and proteomic biomarkers in the drug R&D process. InChemical Genomics and Proteomics, Second Edition (pp. 123-142). CRC Press.

2011

Guergova-Kuras, M., Kurucz, I., Hempel, W., Tardieu, N., Kádas, J., Malderez-Bloes, C., … Takács, L. (2011). Discovery of Lung Cancer Biomarkers by Profiling the Plasma Proteome with Monoclonal Antibody Libraries. Molecular & Cellular Proteomics  (doi: 10.1074/mcp.M111.010298)

Kovács A, Sperling E, Lázár J, Balogh A, Kádas J, Szekrényes A, Takács L, Kurucz I, Guttman A. Fractionation of the human plasma proteome for monoclonal antibody proteomics-based biomarker discovery. Electrophoresis. 2011 Aug;32(15) 1916-1925. doi:10.1002/elps.201100018. PMID: 21732557.

Guergova-Kuras, Mariana Mariana, Istvan Kurucz, William Hempel, Nadege Tardieu, Janos Kadas, Carole Carole Malderez-Bloes, Yann Kieffer, Anne Jullien, Eszter Csanky, and Laszlo Takacs. “Discovery and validation of a plasma protein biomarker panel for early detection of non small cell lung cancer.” in journal of thoracic oncology, vol. 6, no. 6, pp. S1339-s1339. 530 walnut st, philadelphia, pa 19106-3621 usa: lippincott williams & wilkins, 2011.

Takacs, L., Guergova-Kuras, M., Kurucz, I., Tardieu, N., Kadas, J., Malderez-Bloes, C., … & Karger, B. (2011, May). Non-small cell lung cancer biomarkers: Discovery using mab proteomics. In ASCO Annual Meeting Proceedings (Vol. 29, No. 15_suppl, p. 10561).

Poliska, S., Csanky, E., Szanto, A., Szatmari, I., Mesko, B., Szeles, L., … & Takacs, L. (2011). Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function. Respiration, 81(6), 499-510. (doi: 10.1159/000324297)

2010

Wang, D., Hincapie, M., Guergova-Kuras, M., Kadas, J., Takacs, L., & Karger, B. L. (2010). Antigen identification and characterization of lung cancer specific monoclonal antibodies produced by mAb proteomics. Journal of proteome research, 9(4), 1834-1842. (doi: 10.1021/pr900997z)

M Guergova-Kuras, I Kurucz, W Hempel, N Tardieu, J Kadas, C Malderez-Bloes, A Jullien, Y Kieffer, M Hincapie, A Guttman, E Csanky, BL Karger, L Takacs (2010, August). Discovery Of Lung Cancer Biomarkers By Profiling The Plasma Proteome With Monoclonal Antibody Proteomics Technology. In Tumor Biology (Vol. 31, Pp. S50-S50). Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands: Springer.

2009

Csanky, E., Rühl, R., Scholtz, B., Vasko, A., Takacs, L., & Hempel, W. M. (2009). Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients and controls. Electrophoresis,30(7), 1228-1234. (doi: 10.1002/elps.200800722)

2007

Kovacs, I., Kadas, J., Takacs, L., Dibo, G. & Guttman, A. 2007, “Preparation and Characterization of Small-Molecule Metabolite Libraries Covalently Attached to Macromolecular Carriers”, Peptide science : proceedings of the …Japanese Peptide Symposium, vol. 2006, pp. 320

Kuras, M., Duval, M. X., Nagy, L., Scholtz, B., Hancock, W., Karger, B., … & Takacs, L. (2007). Monoclonal antibody proteomics: discovery and prevalidation of chronic obstructive pulmonary disease biomarkers in a single step. Electrophoresis, 28, 4401-4406. (doi: 10.1002/elps.200700256)

2006

Guttman, A., Karger, B. L., Hancock, W. S., & Takacs, L. (2006, October). Biomarker discovery by monoclonal antibody proteomics. In Molecular & Cellular Proteomics (Vol. 5, No. 10, pp. S86-S86). 9650 Rockville Pike, Bethesda, Md 20814-3996 Usa: Amer Soc Biochemistry Molecular Biology Inc.

2005

W Hempel, P Olivova, E Rajnavolgyi, B Karger, W Hancock, L Takacs. “Blomarker discovery and validation in one step; Combination of high throughput monoclonal antibody (MAB) and mass spectrometry technologies.” Molecular & Cellular Proteomics. Vol. 4. No. 8. 9650 Rockville Pike, Bethesda, Md 20814-3996 Usa: Amer Soc Biochemistry Molecular Biology Inc, 2005.